Authors' Note: Wernicke's encephalopathy is a brain disorder that often occurs in the context of binge-drinking in poorly nourished alcoholics. As its characteristic manifestations abate, generally following hospital admission, symptoms of an overlapping condition known as Korsakoff's syndrome may become evident. These consist of various types of memory failure, with prominent confabulation (grandiose storytelling, as part of identity-amnesia). Together the two patterns are described as Wernicke-Korsakoff illness. The treatment for both stages is high-dose thiamine (vitamin B1), administered either intravenously or intramuscularly.
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