September 25, 2021
SEP 25, diagnostic imaging: dipyridamole for stress myocardial perfusion imaging
Tests of myocardial flow in the Nuclear laboratory, e.g. gated SPECT, require a stimulus so that the specific radiotracer can be injected at peak blood flow to image the state of heart muscle. Ideally, exercise stress, as with a submaximal treadmill procedure, provides this stimulus, with a high attained heart rate reflecting success. As a backup in those unable to exercise sufficiently, (musculoskeletal or breathing problems, reduced fitness), pharmacologic stress may be used. Dipyridamole ,tradename Persantine, is a commonly used agent for this purpose, increasing blood flow optimally, but with little change in heart rate or blood pressure.
You can review all our verses on this intriguing topic by proceeding to a post on 'Edifying Nonsense' entitled 'Selected Topics in Diagnostic Imaging'. Click HERE!